看见一个 Expert Review of Anticancer Therapy。你们前面用依维莫斯，血、肝肾功能还好。下一步是否考虑索拉非尼+依维莫斯。供你参考。4 B6 N" W3 @, W9 b0 p5 P
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Currently available feasibility data for possible combination strategies.
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Combination Feasibility according to preliminary data " L) V( {4 r1 m& i: D1 P
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, w4 k# w" i, x2 v' s! C* TBevacizumab + sorafenib Yes, reduced dose ) r) v; s( ~. b: V: w2 X
Bevacizumab + sunitinib† No
# M8 I( G ^4 o5 j# lBevacizumab + temsirolimus Yes
* \1 ?( N3 F3 c; n1 h, bBevacizumab + everolimus Yes 4 R; r0 h: l8 _$ `. f2 m
Sorafenib + sunitinib ?
* H1 u% g4 f9 [5 USorafenib + temsirolimus Yes, reduced dose
) j4 s9 l2 |+ S; x s% TSorafenib + everolimus Yes, reduced dose 5 g0 g' |) @: C( m3 f, i) K$ O" r
Sunitinib + temsirolimus† No / m% O7 h( s5 `: v
Sunitinib + everolimus ?
2 r; e. w% c/ \# K# q/ h& |8 _Temsirolimus + everolimus ?
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†Led to US FDA warning.: B* y0 g: G1 Z$ w$ K$ Y$ V
?: As yet unattempted combination.
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